Day one, March 14th, 2013

 Get together 10:30 h – 11:00 h



Ulrich Mahlknecht, Conference Organizer


Welcome Speeches

Hans-Ulrich Giesen, MD

St. Lukas Klinik Solingen, Medical Director


Keynote Speakers


11:00 h – 11:30 h


Genetic disruption of Epigenetic Enzymes in Cancer


11:30 h – 12:00 h

Javier CAMPION, University of Navarra, Pamplona, Spain

Epigenetic changes involved in obesity and associated comorbidities


12:00 h – 12:30 h

Stefano CASOLA, IFOM - FIRC Inst. of Molecular Oncology, Milan, Italy

Role of the Polycomb axis in adaptive B-cell immunity and Non-Hodgkin B-cell lymphomas


12:30 h – 13:00 h

Renée DUFAULT, Food Ingredient and Health Research Inst., Hawaii, USA

Macroepigenetic model for autism


Coffee break 13:00 h – 13:30 h

13:30 h – 14:00 h

Robert FEIL, University of Montpellier, Montpellier, France 

Genomic imprinting: epigenetic mechanisms and clinical implications


14:00 h – 14:30 h

Eckart MEESE, Saarland University, Homburg, Germany

The blood-borne miRNome in human diseases such as cancer


14:30 - 15:00 h

Alexandra Henrion Caude, Hôpital Necker-Enfants Malades, Paris, France 

Is non-coding RNA a key to uncover gene-environment interaction? 


15:00 h – 15:30 h

Takeo KUBOTA, University of Yamanashi, Yamanashi, Japan

Epigenetics in Neurodevelopmental disorders


Coffee break 15:30 h – 16:00 h

16:00 h – 16:30 h

Ullrich WÜLLNER, University of Bonn, Dept. of Neurology, Bonn, Germany

Methylation profiling in Parkinson's disease


16:30 h – 17:00 h

Wolfgang SCHULZ, Heinrich-Heine-University, Düsseldorf, Germany

Deregulation of imprinted genes in cancer – epigenetic chaos or functional selection


17:00 h – 17:30 h

Michael SCHNEKENBURGER, Hôpital Kirchberg, Luxembourg

Epigenetic alterations in leukemia: a target for DNA demethylating drugs

17:30 h – 18:00 h

Anna KARPATHAKIS, University College London, London, UK

Neuroendocrine Tumors - Cracking the Epigenetic Code


20:00 Dinner


 Day two, March 15th, 2013


9:00 h – 9:30 h

Thomas HAAF, University of Würzburg, Würzburg, Germany 

Epigenetics of gestational diabetes mellitus: how intrauterine life conditions influence later life


9:30 h – 10:00 h

Clara NERVI, University of Rome "La Sapienza", Rome, Italy

The epigenetic role of microRNA-223 in normal and leukemic hematopoiesis

10:00 h – 10:30 h

Arpad PATAI,Semmelweis University, Budapest, Hungary

Colorectal cancer epigenetics: lost in translation?


Coffee break 10:30 h – 11:00 h


11:00 h – 11:30 h

Svend PETERSEN-MAHRT, IFOM-Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy

DNA Deaminases for Epigenetics in Immunity and Cancer


11:30 h – 12:00 h

Monika PUZIANOWSKA-KUZNICKA, Warsaw University, Warsaw, Poland

Epigenetics of immunosenescence


12:00 h – 12:30 h

Hedwig DEUBZER, DKFZ Heidelberg, Heidelberg, Germany

Functions of histone deacetylases in neuroblastoma: implications for disease and therapy


Lunch break 12:30 h – 13:30 h


13:30 h – 14:00 h

Marianne ROTS, University of Groningen, TheNetherlands

Speaking is silver, Silence is golden? Epigenetic Editing to permanently modulate a gene's expression level


14:00 h – 14:30 h

Gunnar SCHOTTA, Ludwig-Maximilian-University, Munich, Germany

Epigenetic regulation of lineage decisions


14:30 h – 15:00 h

Toshikazu USHIJIMA, National Cancer Center Research Institute, Tokyo, Japan

Inflammation and epigenetic field for cancerization


Coffee break 15:00 h – 15:30 h


15:30 h – 16:00 h

Jonathan D. TURNERCRP-Santé, Dept. Immunology,  Luxembourg

Epigenetic regulation of Glucocorticoid receptor promoters both controls, and is controlled by, the hypothalamus-pituitary-adrenal axis.


16:00 h – 16:30 h

Erica WATSON, University of Cambridge, Cambridge, UK 

Epigenetic inheritance of congenital malformations caused by abnormal folate metabolism


16:30 h – 17:00 h 

Nick LaTHANGUE, University of Oxford, Dept. of Oncology, Oxford, UK

Therapeutic application of HDAC inhibitors



Ulrich Mahlknecht

Concluding remarks, end of congress